![]() Endogenous retroviruses have been key to our evolution and for the regulation of gene expression, and the gut microbiota helps us digest compounds that we could not otherwise process. ![]() Nevertheless, it is clear that we could not live in a world without these tiny beings. Viruses and bacteria have written or decisively contributed to terrible episodes of history, such as the Black Death in 14th century Europe, the annihilation of pre-Columbian American civilizations, and pandemics such as the 1918 Spanish flu or the current COVID-19 pandemic caused by the coronavirus SARS-CoV-2. This evolution is associated with multiple factors, among which the role of microorganisms is often overlooked. ![]() Universal history is characterized by continuous evolution, in which civilizations are born and die.
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